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- Title
Vaccine strain Listeria monocytogenes bacteremia occurring 31 months after immunization.
- Authors
Salinas, Linda J.; Fares, Elias; Drevets, Douglas A.; McCloskey, Cindy B.; Gutierrez, Andres; Princiotta, Michael
- Abstract
Background: Listeria monocytogenes is a food-borne, facultative intracellular bacterium that causes severe diseases such as sepsis and meningoencephalitis in immunocompromised hosts. Because it stimulates robust T-lymphocyte-mediated responses, attenuated L. monocytogenes are candidate vaccine vectors for tumor immunotherapy. Case: We report a case of bacteremia caused by vaccine strain L. monocytogenes (Axalimogene filolisbac) occurring 31 months after immunization against human papilloma virus (HPV) associated cervical cancer. Conclusion: Receipt of a L. monocytogenes-based vaccine is a novel risk factor for delayed L. monocytogenes bacteremia.
- Subjects
BACTEREMIA diagnosis; PAPILLOMAVIRUS disease prevention; LISTERIOSIS; BACTEREMIA; IMMUNOTHERAPY; THERAPEUTIC complications; CERVIX uteri tumors; HUMAN papillomavirus vaccines; DISEASE risk factors
- Publication
Infection, 2019, Vol 47, Issue 3, p489
- ISSN
0300-8126
- Publication type
Article
- DOI
10.1007/s15010-018-1249-7