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- Title
Multiple checkpoints ensure ribosomes have the correct end.
- Authors
Gordon, Jacob; Stanley, Robin E.
- Abstract
The 3′ end of the 18S ribosomal RNA is formed by the endoribonuclease Nob1. How cells ensure the accuracy of the 3′ end has remained a mystery. A new study in PLOS Biology revealed that there are multiple checkpoints to ensure that only ribosomes containing the correct 3′ end participate in translation. The 3' end of 18S ribosomal RNA is formed by the endoribonuclease Nob1, but how cells ensure the accuracy of the 3' end has been a mystery. A new study in PLOS Biology has revealed multiple checkpoints that ensure only ribosomes containing the correct 3' end participate in translation.
- Subjects
RIBOSOMAL RNA; RIBOSOMES; RIBOSOMAL proteins; BIOLOGY
- Publication
PLoS Biology, 2024, Vol 22, Issue 4, p1
- ISSN
1544-9173
- Publication type
Article
- DOI
10.1371/journal.pbio.3002603