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- Title
Core needle biopsy can minimise the non-diagnostic results and need for diagnostic surgery in patients with calcified thyroid nodules.
- Authors
Ha, Eun; Baek, Jung; Lee, Jeong; Kim, Jin; Kim, Jae; Lim, Hyun; Song, Dong; Sung, Tae; Kim, Tae; Kim, Won; Shong, Young
- Abstract
Purpose: To evaluate the role of core needle biopsy (CNB) for calcified thyroid nodules. Methods: Between October 2008 and July 2011, 264 patients underwent ultrasound-guided CNB for 272 calcified thyroid nodules at our institution. We retrospectively evaluated the incidence of technical failure, non-diagnostic readings, and the diagnostic performance of CNB, and analysed the relationship between the types of calcification and the CNB results. Finally, the incidence of diagnostic surgery was calculated. Results: The incidence of technical failure was 1.1 % (3/275) and that of non-diagnostic results was 0.7 % (2/272). The diagnostic accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of CNB were 94.7 %, 89.5 %, 100 %, 100 %, and 90.2 %, respectively. There were no significant differences according to the calcification subtype for either the non-diagnostic results or the incidence of technical failure ( P > 0.99 and P > 0.99). CNB could prevent diagnostic surgery for 92.9 % (13/14) of the patients who showed more than two non-diagnostic results in previous FNA. Conclusions: CNB can minimise the non-diagnostic results as well as diagnostic surgery in patients with calcified thyroid nodules. Therefore, CNB may be used as a first-line diagnostic tool for calcified thyroid nodules rather than FNA. Key points: • CNB results show the low incidence of technical failure (1.1 %, 3/275). • CNB results show the low non-diagnostic rate (0.7 %, 2/272). • There were no significant differences according to the calcification subtype. • CNB can prevent unnecessary diagnostic surgery in 92.9 % (13/14).
- Subjects
NEEDLE biopsy; THYROID gland tumors; SURGERY; CALCIFICATION; DIAGNOSIS
- Publication
European Radiology, 2014, Vol 24, Issue 6, p1403
- ISSN
0938-7994
- Publication type
Article
- DOI
10.1007/s00330-014-3123-z