We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Thyroxine treatment induces upregulation of renin‐angiotensin‐aldosterone system due to decreasing effective plasma volume in patients with primary myxoedema.
- Authors
Park, Cheol Whee; Shin, Young Shin; Ahn, Seog Ju; Kim, Suk Young; Choi, Eui Jin; Chang, Yoon Sik; Bang, Byung Kee
- Abstract
Background. In experimental animals and humans, hypothyroidism is associated with fluid retention and generalized oedema, increased antidiuretic hormone (ADH), decreased atrial natriuretic hormone (ANH), and decreased renin‐angiotensin‐aldosterone system (RAAS), which subsequently can be corrected by thyroid hormone replacement. The purpose of this study was to determine the effect of thyroxine therapy on RAAS and neurohormones affecting water and electrolyte metabolism and the reason for these changes in patients with primary myxoedema.
- Publication
Nephrology Dialysis Transplantation, 2001, Vol 16, Issue 9, p1799
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/16.9.1799