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- Title
Alt Ekstremite Periferik Arter Hastalığı Ciddiyetini Göstermede Yeni Bir Parametre: Eritrosit Dağılım Genişliği/Albümin Oranı.
- Authors
ALGÜL, Engin; ÖZBEYAZ, Nail Burak; ŞAHAN, Haluk Furkan; AYDINYILMAZ, Faruk; PAMUKCU, Hilal Erken
- Abstract
Objective: Red cell distribution width (RDW) and albumin levels are important predictors of atherosclerotic diseases. The RDW/Albumin ratio (RAR) is a new ratio defined to have a higher predictive value by using these two parameters together. In our study, we aimed to investigate the relationship between RAR and disease severity in patients with lower extremity peripheral artery disease (LEPAD). Material and Method: For the study, 293 patients who underwent conventional invasive lower extremity peripheral angiography were retrospectively screened and 186 patients with at least one lesion were included in the study. Patients were divided into two groups according to the severity of LEPAD using the TransAtlantic Inter-Society Consensus-II (TASC-II) classification. The RAR was obtained by dividing the RDW by the albumin level. Results: While there were TASC A-B lesions in 86 (Group 1) of the patients included in the study, TASC C-D lesions were detected in 100 (Group 2). RDW value and albumin level were found to be significantly lower in group 2 compared to group 1 (respectively; 14.5±1.5 vs. 15.5±2.7, p=0.005; 38.4±5.1 vs. 33.2±7.2, p<.001) RAR was found to be significantly higher in group 2 (0.38±0.07 vs. 0.49±0.13, p <0.001). In multivariate regression analysis, RAR (RO=3.851(1.483-7.542), p<.001) was found to be an independent predictor of increased LEPAD severity. Conclusion: Increased RDW/albumin ratio was associated with angiographically increased PAH severity in LEPAD patients. The RDW/albumin ratio may be useful in identifying these patients and managing their treatment.
- Publication
MN Cardiology / MN Kardiyoloji, 2024, Vol 31, Issue 1, p15
- ISSN
1300-4778
- Publication type
Article