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- Title
Alleskönner Vitamin D?
- Authors
Unholzer, S.; Rothmund, A.; Haen, E.
- Abstract
Background: Many indications are discussed for vitamin D substitution, such as osteoporosis, autoimmune diseases, cancer and psychiatric diseases. Also discussed is the fact that the majority of the German population suffer from a vitamin D deficiency. Objective: Review of the study results for these individual diseases and a critical analysis of the currently established therapeutic reference range, which defines a vitamin D deficiency. Material and methods: A literature search was carried out in the statements of the German Society for Nutrition, in scientific publications and journals. Results: The study results on prevention and therapy of various diseases with vitamin D show inconsistent results. Well-established indications are the prevention of rickets in babies and the supportive therapy for osteoporosis. The currently established reference range for the definition of a vitamin D deficiency came from studies where vitamin D deficiency was correlated to an increase in parathyroid hormone. Different laboratories use different methods for measurement of vitamin D levels. Conclusion: More studies are needed to clarify the role of vitamin D in the prevention and treatment of various diseases. Another problem is that different laboratories do not use the same measurement methods to determine vitamin D and the use of different methods leads to widely varying results which cannot be compared. Therefore, a standardization of the methods would be desirable.
- Publication
Der Nervenarzt, 2017, Vol 88, Issue 5, p489
- ISSN
0028-2804
- Publication type
Article
- DOI
10.1007/s00115-016-0278-7