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- Title
PREDICTION OF ADME-TOX PROPERTIES OF POLYLACTIC ACID OLIGOMERS.
- Authors
Roman, Diana Larisa; Roman, Marin; Ceauranu, Silvana; Ostafe, Vasile; Isvoran, Adriana
- Abstract
Within this study we reveal the ADME-Tox properties and pharmacokinetics of polylactic acid oligomers: aqueous solubility, skin permeation, blood brain barrier permeation, substrate/inhibitor of the human cytochromes P450 mainly involved in xenobiotics metabolism, carcinogenicity, mutagenicity. Information concerning these properties becomes important as these oligomers have numerous applications in medical and pharmaceutical industries.
- Subjects
POLYLACTIC acid; PHARMACOKINETICS; OLIGOMERS; XENOBIOTICS; PHARMACEUTICAL industry
- Publication
New Frontiers in Chemistry, 2018, Vol 27, Issue 1, p36
- ISSN
2393-2171
- Publication type
Article