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- Title
Diagnostic utility of Tzanck Smear in various cutaneous skin infections.
- Authors
S., Kamble; S., Deshpande; A., Kagal; R., Bharadwaj
- Abstract
Aim: Tzanck smear is a simple test that gives reliable information in many of skin lesions and can be used for quick, presumptive diagnosis of a number of cutaneous infections. The aim of this study was to see the usefulness of tzanck smears in the diagnosis of cutaneous skin infections Materials and Methods: Retrospective analysis of all tzanck smears received during the time period of (January 2016-March 2018), was carried out. Aspirates were collected from the clinically suspected skin lesions, smears were prepared and stained with Giemsa stain and evaluated, The smears were observed with the clinical correlation of the diagnosis of patient. Results: A total of 100 tzanck smears were performed during our study period. Out of 19 cases of vesiculobullous lesions the tzanck smear positivity was seen in 4 cases, out of 35 Herpes viral infection cases 9 were positive by tzanck smear. Phemphigus group showed positivity of 15 out of 40 cases. Others (Pellagra, papillosis, Steven Johnson syndrome, Molluscum contagiosum, Contact dermatitis) 6 cases were also included in the study which showed no positivity to tzanck smears. In our study the positivity of Tzanck smears was 28%.Most of the patients were on antiviral therapy Acyclovir and responded to treatment. Conclusion: Tzanck smear test is a rapid, inexpensive and useful test to aid in the diagnosis of clinically suspected vesico bullous, pustular and erosive skin lesions. It also serves as a useful adjunct to histopathological evaluation of skin biopsies, especially immuno-bullous skin disorders.
- Subjects
JOHNSON, Steven, 1968-; SKIN infections; DIAGNOSIS; VIRUS diseases; CONTACT dermatitis; HERPESVIRUS diseases
- Publication
Indian Journal of Basic & Applied Medical Research, 2020, Vol 10, Issue 1, p199
- ISSN
2250-284X
- Publication type
Article
- DOI
10.36848/IJBAMR/2020/16215.55705