We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
IN VITRO CYTOPHYSIOLOGICAL RESPONSE INDUCED BY THREE FOOD ADDITIVES ON SOME MAMMALIAN CELL LINE MODELS.
- Authors
Gherghel, Daniela; Mihai, Cosmin-Teodor; Vochița, Gabriela; Roșu, Crăița-Maria
- Abstract
This research is focused on cellular response to sodium metabisulfite (E223), sodium benzoate (E211), and sodium nitrite (E250) application on two normal mammalian cell lines, namely MCF-12A (ATCC CRL-3598) and Vero (ATCC CCL-81). The monitored parameters were cell viability (MTT assay), cell morphology (optical microscopy) and cell survival (clonogenic assay). The treatment was applied in doses of 12.5; 25; 50 and 100 Î?g/mL. According to all applied tests, our results proved a dose-response relationship, the MCF-12A cell line showing the highest sensitivity.
- Subjects
FOOD additives; CELL morphology; SODIUM nitrites; SODIUM benzoate; MICROSCOPY
- Publication
Journal of Experimental & Molecular Biology, 2024, Vol 25, Issue 1, p21
- ISSN
2601-6974
- Publication type
Article
- DOI
10.47743/jemb-2024-149