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- Title
TECHNIQUES AND ALGORITHMS FOR STRUCTURE-BASED VIRTUAL SCREENING (SBVS): AN OVERVIEW.
- Authors
Raoa, Raksha K.; Chaudhari, Somdatta Y.; Jadhav, Shailaja B.; Chaudhari, Pravin D.; Yedake, Ujwala B.
- Abstract
Today, the world of science is constantly challenged with new genomics, which in turn is responsible for new disease-causing targets. Hence, there is a need for developing drugs acting against such targets. Computational methods are proving to be a mainstay in the drug discovery process, mainly through virtual screening. This review discusses about the recent advancements in structure-based drug design with reference to Virtual Screening along with its procedures from ligand preparation and protein preparation, docking, scoring function, databases, and virtual (VS) algorithms. Application of Structure-based VS in combination with other virtual screening techniques has also been highlighted in this review.
- Subjects
DRUG discovery; DRUG design; ALGORITHMS; VIRTUAL design; NUTRITIONAL genomics
- Publication
Indian Drugs, 2024, Vol 61, Issue 1, p7
- ISSN
0019-462X
- Publication type
Article
- DOI
10.53879/id.61.01.13346