We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
急性冠脉综合征患者GRACE评分与心功能及冠脉病变的关系研究.
- Authors
王胜强; 赵爱荣; 李吉刚; 张俭; 徐倩
- Abstract
To investigate the relationship between the global acute coronary disease registration (GRACE) risk score and cardiac function and coronary artery lesions in patients with acute coronary syndrome (ACS). Methods: The clinical data of 276 patients with ACS, who were treated in 148th Central Hospital of PLA from April 2015 to June 2017, were analyzed retrospectively and divided into high risk group (n=93. GRACE score over 140 points), middle risk group (n=96. GRACE score between 109-140 points) and low risk group (n=87. GRACE score less than 109 points) according to the GRACE score. The general data, biochemical indexes, cardiac function indexes and severity of coronary lesions were compared among the three groups. The spearman correlation coefficient was used to analyze the correlation between GRACE score and cardiac function index and severity of coronary lesions. Results: The proportion of men, age. hypertension, ratio of apolipoprotein -B (Apo-B). fasting blood glucose (FBG). fibrinogen (FIB). Cystatin -C (Cys-C). homocysteine (Hey), left atrial diameter (LAAP). end systolic diameter left ventricular (LVESD). left ventricular end diastolic diameter (LVEDD), multi vessel disease and the proportion of severe stenosis and complete occlusion of the proportion in the high risk group and the middle risk group were higher than those in the low risk group, and the high risk group was higher than the middle risk group.the differences were statistically significant (P<0.05). The levels of TG. Apo-A and LVEF in the high risk group and the middle risk group were lower than those in the low risk group, the differences were statistically significant (P<0.05). Spearman correlation coefficient analysis showed that there was a positive correlation between GRACE score and LAAP. LVESD. LVEDD. the number of coronary lesions and the degree of stenosis (P<0.05) and there was a negatively correlation between the GRACE score and the level of LVEF (P<0.05). Conclusion: The higher the GRACE score, the worse the heart function in ACS patients and the severity of coronary disease. The GRACE score can reflect the cardiac function level and the severity of coronary artery disease in ACS patients.
- Publication
Progress in Modern Biomedicine, 2017, Vol 17, Issue 31, p6175
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2017.31.041