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- Title
血浆D- 二聚体、纤维蛋白原水平与骨创伤患者创伤程度的相关性.
- Authors
谢涛江; 蓝勇波; 张彤; 孙川江; 刘斐文; 罗翼
- Abstract
Objective: To investigate the correction of plasma D-dimer, fibrinogen levels with the traumatic degree of patients with orthopedic trauma. Methods: One hundred and eighty patients with orthopedic trauma in our hospital from January 2015 to January 2016 were selected as the observation group, and one hundred healthy people in the same period were chosen as the control group. The plasma D-dimer and fibrinogen levels from 1st to 10th day after admission were compared, and the correction of plasma D-dimer (DD), fibrinogen (FIB) levels with the traumatic degree were analyzed. Results: The DD and FIB levels in observation group were obviously lowered, which were significantly higher than those of the control group (P<0.05). The DD and FIB levels in serious injury group and moderated injury group were much higher than those of the slight injury group, and those in serious injury group was the highest (P<0.05). And DD and FIB levels in the three groups had a remarkable decrease from 1st to 10th day (P<0.05). Additionally, plasma D-dimer and fibrinogen levels were significantly and positively correlated with the orthopedic traumatic degree (r=0.64, P=0.003;r=0.71, P=0.002). Conclusion: The levels of plasma DD and FIB in patients with orthopedic trauma were markedly higher than those of the healthy people, which were significantly and positively correlated with the orthopedic traumatic degree and could be served as a biomarker on assessment of traumatic degree and prognosis.
- Publication
Progress in Modern Biomedicine, 2017, Vol 17, Issue 15, p2934
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2017.15.035