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- Title
The Antioxidant and Anti-inflammatory Properties of Chamomile and Its Constituents.
- Authors
Talebi, Saeedeh; Sharifan, Payam; Ostad, Andisheh Norouzian; Shariati, Seyedeh Elaheh; Ghalibaf, AmirAli Moodi; Barati, Mehdi; Aghasizadeh, Malihe; ghoflchi, Sahar; Ghazizadeh, Hamideh; Shabani, Niloofar; Ferns, Gordon. A.; Rahimi, Hamid Reza; Mobarhan, Majid Ghayour
- Abstract
Introduction: An imbalance has been reported in the oxidant-antioxidant system of infants with febrile convulsion. This study aimed to compare serum vitamin C levels between febrile children with or without seizures. Methods: This multicenter case-control study was conducted on febrile infants and children referred to Mashhad University of Medical Sciences pediatric emergency wards. The subjects were equally divided into two febrile groups of case (with seizures) and control (without seizures). A visible spectrophotometer was used to determine the total vitamin C level. Results: In total, 100 febrile children were included in the study. Based on the results, there was no statistically significant difference between the two groups in terms of age, gender, and family history of febrile convulsion (FC) (P>0.05). The mean vitamin C levels in the case and control groups were 42.73±7.2 and 78.59±11.1 Hg/1, respectively. There was a significant difference between the groups regarding the vitamin C level (P<0.001). Regression analysis revealed that age (P=0.74), gender (P=0.66), and family history of febrile convulsion (P=0.52) had not any correlation with vitamin C levels. On the other hand, vitamin C levels were associated with FC (P=0.001). Conclusion: The serum levels of vitamin C were lower in children with febrile seizures than in the control group. Thus, reduced vitamin C levels can be considered a predisposing factor for FC.
- Subjects
VITAMIN C; FEBRILE seizures; AGE groups; PEDIATRIC emergencies; REGRESSION analysis
- Publication
Reviews in Clinical Medicine, 2022, Vol 9, Issue 3, p110
- ISSN
2345-6256
- Publication type
Article