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- Title
The MTHFD1L Gene rs11754661 Marker is Not Associated with Alzheimer's Disease in a Sample of the Spanish Population.
- Authors
Ramírez-Lorca, Reposo; Boada, Mercé; Antúnez, Carmen; López-Arrieta, Jesús; Moreno-Rey, Concha; Hernández, Isabel; Marín, Juan; Gayán, Javier; González-Pérez, Antonio; Alegret, Montserrat; Tárraga, Lluis; Real, Luis M.; Ruiz, Agustín
- Abstract
The MTHFD1L gene SNP variant rs11754661 was found to increase the risk of Alzheimer's disease in a recent Whole Genome Association Study [1]. We have carried out an independent study of this genetic variant in 2467 individuals from Spain. We found no evidence of association between the MTHFD1L marker and susceptibility to Alzheimer's disease in our sample.
- Subjects
SPAIN; VITAMIN B complex; FOLIC acid; HOMOCYSTEINE; POPULATION genetics; DISEASE susceptibility; ALZHEIMER'S disease; GENES
- Publication
Journal of Alzheimer's Disease, 2011, Vol 25, Issue 1, p47
- ISSN
1387-2877
- Publication type
Article
- DOI
10.3233/JAD-2011-101983