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- Title
The Hepatitis B Virus Genotypes E to J: The Overlooked Genotypes.
- Authors
Toyé, Rayana Maryse; Loureiro, Carmen Luisa; Jaspe, Rossana Celeste; Zoulim, Fabien; Pujol, Flor Helene; Chemin, Isabelle
- Abstract
Hepatitis B virus (HBV) genotypes E to J are understudied genotypes. Genotype E is found almost exclusively in West Africa. Genotypes F and H are found in America and are rare in other parts of the world. The distribution of genotype G is not completely known. Genotypes I and J are found in Asia and probably result from recombination events with other genotypes. The number of reported sequences for HBV genotypes E to J is small compared to other genotypes, which could impact phylogenetic and pairwise distance analyses. Genotype F is the most divergent of the HBV genotypes and is subdivided into six subgenotypes F1 to F6. Genotype E may be a recent genotype circulating almost exclusively in sub-Saharan Africa. Genotype J is a putative genotype originating from a single Japanese patient. The paucity of data from sub-Saharan Africa and Latin America is due to the under-representation of these regions in clinical and research cohorts. The purpose of this review is to highlight the need for further research on HBV genotypes E to J, which appear to be overlooked genotypes.
- Subjects
SUB-Saharan Africa; HEPATITIS B virus; GENOTYPES; DISTANCES
- Publication
Microorganisms, 2023, Vol 11, Issue 8, p1908
- ISSN
2076-2607
- Publication type
Article
- DOI
10.3390/microorganisms11081908