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- Title
P. falciparum Invasion and Erythrocyte Aging.
- Authors
Alves-Rosa, María Fernanda; Tayler, Nicole M.; Dorta, Doriana; Coronado, Lorena M.; Spadafora, Carmenza
- Abstract
Plasmodium parasites need to find red blood cells (RBCs) that, on the one hand, expose receptors for the pathogen ligands and, on the other hand, maintain the right geometry to facilitate merozoite attachment and entry into the red blood cell. Both characteristics change with the maturation of erythrocytes. Some Plasmodia prefer younger vs. older erythrocytes. How does the life evolution of the RBC affect the invasion of the parasite? What happens when the RBC ages? In this review, we present what is known up until now.
- Subjects
ERYTHROCYTES; PLASMODIUM; ERYTHROCYTE deformability; LIGANDS (Biochemistry)
- Publication
Cells (2073-4409), 2024, Vol 13, Issue 4, p334
- ISSN
2073-4409
- Publication type
Article
- DOI
10.3390/cells13040334