Results: 2373
(THIO)XANTHONES-MEDIATED P-GLYCOPROTEIN ACTIVATION: AN IN SILICO STUDY.
- Published in:
- Revista de Toxicología, 2024, v. 41, n. 2, p. 107
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- Publication type:
- Article
Bioenhancer Herbs: Natural Agents for Optimizing Drug Efficacy and Bioavailability.
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- Journal of Ravishankar University, Part-B Science, 2024, v. 37, n. 2, p. 96, doi. 10.52228/JRUB.2024-37-2-9
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- Publication type:
- Article
Hemin Promotes Higher Effectiveness of Aminolevulinic-Photodynamic Therapy (ALA-PDT) in A549 Lung Cancer Cell Line by Interrupting ABCG2 Expression.
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- Medical Sciences, 2024, v. 12, n. 4, p. 66, doi. 10.3390/medsci12040066
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- Publication type:
- Article
Influence of Intermittent Hypoxia on Myocardial and Hepatic P-glycoprotein Expression in a Rodent Model.
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- Pharmacotherapy, 2009, v. 29, n. 4, p. 365, doi. 10.1592/phco.29.4.365
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- Publication type:
- Article
Lack of Effect of P-glycoprotein Inhibition on Renal Clearance of Dicloxacillin in Patients with Cystic Fibrosis.
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- Pharmacotherapy, 2008, v. 28, n. 7, p. 883, doi. 10.1592/phco.28.7.883
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- Publication type:
- Article
Decreased Serum Linezolid Levels in a Critically Ill Patient Receiving Concomitant Linezolid and Rifampin.
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- Pharmacotherapy, 2007, v. 27, n. 3, p. 476, doi. 10.1592/phco.27.3.476
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- Article
Tachycardia-Induced Heart Failure Does Not Alter Myocardial P-glycoprotein Expression.
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- Pharmacotherapy, 2004, v. 24, n. 1, p. 1
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- Publication type:
- Article
Effects of Grapefruit Juice on Intestinal P-glycoprotein: Evaluation Using Digoxin in Humans.
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- Pharmacotherapy, 2003, v. 23, n. 8, p. 979, doi. 10.1592/phco.23.8.979.32881
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- Publication type:
- Article
Evaluation of P-glycoprotein-Mediated Renal Drug Interactions in an NDR1-MDCK Model.
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- Pharmacotherapy, 2003, v. 23, n. 4, p. 436, doi. 10.1592/phco.23.4.436.32125
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- Publication type:
- Article
Investigations on the cell metabolomics basis of multidrug resistance from tumor cells by ultra-performance liquid chromatography-mass spectrometry.
- Published in:
- Analytical & Bioanalytical Chemistry, 2016, v. 408, n. 21, p. 5843, doi. 10.1007/s00216-016-9696-4
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- Article
Development of a Library of Thiophene‐Based Drug‐Like Lego Molecules: Evaluation of Their Anion Binding, Transport Properties, and Cytotoxicity.
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- Chemistry - A European Journal, 2020, v. 26, n. 4, p. 888, doi. 10.1002/chem.201904255
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- Publication type:
- Article
Highly Potent and Intestine Specific P‐Glycoprotein Inhibitor to Enable Oral Delivery of Taxol.
- Published in:
- Angewandte Chemie, 2024, v. 136, n. 45, p. 1, doi. 10.1002/ange.202412649
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- Publication type:
- Article
A Photoinduced, Nickel‐Catalyzed Reaction for the Stereoselective Assembly of C‐Linked Glycosides and Glycopeptides.
- Published in:
- Angewandte Chemie, 2023, v. 135, n. 5, p. 1, doi. 10.1002/ange.202214247
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- Publication type:
- Article
Hyperfluorescence Imaging of Kidney Cancer Enabled by Renal Secretion Pathway Dependent Efflux Transport.
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- Angewandte Chemie, 2021, v. 133, n. 1, p. 355, doi. 10.1002/ange.202010187
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- Article
Exploring Ovarian Cancer Cell Resistance to Rhenium Anticancer Complexes.
- Published in:
- Angewandte Chemie, 2020, v. 132, n. 32, p. 13493, doi. 10.1002/ange.202004883
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- Article
Potential of nanostructured lipid carriers in oral delivery of the poorly soluble drugs.
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- Journal of Nanoparticle Research, 2023, v. 25, n. 9, p. 1, doi. 10.1007/s11051-023-05840-0
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- Article
Computational design, synthesis and evaluation of new sulphonamide derivatives targeting HIV-1 gp120.
- Published in:
- Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 1, p. 39, doi. 10.1007/s10822-019-00258-0
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- Publication type:
- Article
Prediction of P-glycoprotein inhibitors with machine learning classification models and 3D-RISM-KH theory based solvation energy descriptors.
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- Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 11, p. 965, doi. 10.1007/s10822-019-00253-5
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- Publication type:
- Article
Boosted feature selectors: a case study on prediction P-gp inhibitors and substrates.
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- Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 11, p. 1273, doi. 10.1007/s10822-018-0171-5
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- Publication type:
- Article
Combined QSAR and molecule docking studies on predicting P-glycoprotein inhibitors.
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- Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 12, p. 1067, doi. 10.1007/s10822-013-9697-8
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- Publication type:
- Article
In silico model for P-glycoprotein substrate prediction: insights from molecular dynamics and in vitro studies.
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- Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 4, p. 347, doi. 10.1007/s10822-013-9650-x
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- Publication type:
- Article
2D- and 3D-QSAR studies of a series of benzopyranes and benzopyrano[3,4b][1,4]-oxazines as inhibitors of the multidrug transporter P-glycoprotein.
- Published in:
- Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 2, p. 161, doi. 10.1007/s10822-013-9635-9
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- Publication type:
- Article
A recursive-partitioning model for blood–brain barrier permeation.
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- Journal of Computer-Aided Molecular Design, 2005, v. 19, n. 7, p. 465, doi. 10.1007/s10822-005-9001-7
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- Publication type:
- Article
Radiosynthesis and preliminary evaluation of an <sup>18</sup>F‐labeled tubastatin A analog for PET imaging of histone deacetylase 6.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2020, v. 63, n. 2, p. 85, doi. 10.1002/jlcr.3823
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- Publication type:
- Article
Tacrolimus induces remission in refractory and relapsing lupus nephritis by decreasing P-glycoprotein expression and function on peripheral blood lymphocytes.
- Published in:
- Rheumatology International, 2022, v. 42, n. 8, p. 1347, doi. 10.1007/s00296-021-05057-1
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- Publication type:
- Article
P-glycoprotein gene MDR1 polymorphisms and susceptibility to systemic lupus erythematosus in Guangxi population: a case-control study.
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- Rheumatology International, 2017, v. 37, n. 4, p. 537, doi. 10.1007/s00296-017-3652-2
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- Publication type:
- Article
An intracerebral microdialysis study to determine the neuropharmacokinetics of eribulin in patients with metastatic or primary brain tumors.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 6, p. 807, doi. 10.1007/s00280-024-04711-2
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- Publication type:
- Article
Continuous 72-h infusion of zosuquidar with chemotherapy in patients with newly diagnosed acute myeloid leukemia stratified for leukemic blast P-glycoprotein phenotype.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2024, v. 93, n. 6, p. 595, doi. 10.1007/s00280-024-04656-6
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- Publication type:
- Article
The Beta2-adrenergic agonist salbutamol synergizes with paclitaxel on cell proliferation and tumor growth in triple negative breast cancer models.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2023, v. 92, n. 6, p. 485, doi. 10.1007/s00280-023-04586-9
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- Publication type:
- Article
Influence of CYP3A5 and ABCB1 polymorphisms on the pharmacokinetics of vincristine in adult patients receiving CHOP therapy.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2023, v. 92, n. 5, p. 391, doi. 10.1007/s00280-023-04580-1
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- Publication type:
- Article
A clinical trial of zosuquidar plus gemtuzumab ozogamicin (GO) in relapsed or refractory acute myeloid leukemia (RR AML): evidence of efficacy based on leukemic blast P-glycoprotein functional phenotype.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2023, v. 92, n. 5, p. 369, doi. 10.1007/s00280-023-04578-9
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- Publication type:
- Article
Effects of splicing-regulatory polymorphisms in ABCC2, ABCG2, and ABCB1 on methotrexate exposure in Chinese children with acute lymphoblastic leukemia.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 1, p. 77, doi. 10.1007/s00280-022-04498-0
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- Publication type:
- Article
Association between gene polymorphism and adverse effects in cancer patients receiving docetaxel treatment: a meta-analysis.
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- 2022
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- Publication type:
- journal article
Mechanistic physiology-based pharmacokinetic modeling to elucidate vincristine-induced peripheral neuropathy following treatment with novel kinase inhibitors.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2021, v. 88, n. 3, p. 451, doi. 10.1007/s00280-021-04302-5
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- Publication type:
- Article
Cabazitaxel is more active than first-generation taxanes in ABCB1(+) cell lines due to its reduced affinity for P-glycoprotein.
- Published in:
- 2018
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- Publication type:
- journal article
Pharmacogenetic study of the impact of ABCB1 single-nucleotide polymorphisms on lenalidomide treatment outcomes in patients with multiple myeloma: results from a phase IV observational study and subsequent phase II clinical trial.
- Published in:
- 2018
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- Publication type:
- journal article
Eribulin shows high concentration and long retention in xenograft tumor tissues.
- Published in:
- 2017
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- Publication type:
- journal article
BSA and ABCB1 polymorphism affect the pharmacokinetics of sunitinib and its active metabolite in Asian mRCC patients receiving an attenuated sunitinib dosing regimen.
- Published in:
- 2016
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- Publication type:
- journal article
Pharmacokinetics, placenta, and brain uptake of paclitaxel in pregnant rats.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 5, p. 1041, doi. 10.1007/s00280-014-2439-3
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- Publication type:
- Article
No clinically significant drug interactions between lenalidomide and P-glycoprotein substrates and inhibitors: results from controlled phase I studies in healthy volunteers.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 5, p. 1031, doi. 10.1007/s00280-014-2438-4
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- Publication type:
- Article
Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 3, p. 635, doi. 10.1007/s00280-012-2050-4
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- Publication type:
- Article
Increased expression and function of P-glycoprotein in peripheral blood CD56+ cells is associated with the chemoresistance of non-small-cell lung cancer.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2012, v. 70, n. 3, p. 365, doi. 10.1007/s00280-012-1915-x
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- Publication type:
- Article
Accumulation and distribution of doxorubicin in tumour spheroids: the influence of acidity and expression of P-glycoprotein.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1179, doi. 10.1007/s00280-011-1598-8
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- Publication type:
- Article
Interaction potential of the endothelin-A receptor antagonist atrasentan with drug transporters and drug-metabolising enzymes assessed in vitro.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 4, p. 1093, doi. 10.1007/s00280-011-1715-8
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- Publication type:
- Article
H1, a novel derivative of tetrandrine reverse P-glycoprotein-mediated multidrug resistance by inhibiting transport function and expression of P-glycoprotein.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 5, p. 1017, doi. 10.1007/s00280-010-1397-7
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- Publication type:
- Article
Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 5, p. 1063, doi. 10.1007/s00280-010-1396-8
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- Publication type:
- Article
PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 4, p. 765, doi. 10.1007/s00280-009-1221-4
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- Publication type:
- Article
Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 3, p. 585, doi. 10.1007/s00280-009-1200-9
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- Publication type:
- Article
MDR1 C2005T polymorphism changes substrate specificity.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 3, p. 617, doi. 10.1007/s00280-010-1308-y
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- Publication type:
- Article
Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 5, p. 867, doi. 10.1007/s00280-007-0676-4
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- Publication type:
- Article