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- Title
Burden of illness in irritable bowel syndrome comparing Rome I and Rome II criteria.
- Authors
Badia, X.; Mearin, F.; Balboa, A.; Baró, E.; Caldwell, E.; Cucala, M.; Díaz-Rubio, M.; Fueyo, A.; Ponce, J.; Roset, M.; Talley, N.J.; Badia, Xavier; Mearin, Fermin; Balboa, Agustin; Baró, Eva; Caldwell, Ellen; Cucala, Mercedes; Díaz-Rubio, Manuel; Fueyo, Arturo; Ponce, Julio
- Abstract
<bold>Objectives: </bold>To evaluate the burden of illness in irritable bowel syndrome (IBS), in terms of resource utilisation (direct and indirect) and health-related quality of life (HR-QOL), in individuals with IBS who meet Rome I and Rome II criteria.<bold>Methods: </bold>A cross-sectional study, carried out by personal interview, on a representative sample (n = 2000) of the Spanish population. Individuals with suspected IBS were identified via a screening question and subsequently given an epidemiological questionnaire to complete. The questionnaire collected information on IBS symptoms, resource utilisation, and HR-QOL [Medical Outcomes Study 36-item Short Form (SF-36)].<bold>Results: </bold>Sixty-five individuals met Rome II criteria for IBS, while 146 individuals met exclusively Rome I criteria. Of Rome II individuals, 67.7% had consulted some type of healthcare professional in the previous 12 months, compared with only 41.8% of those individuals meeting exclusively Rome I criteria (p vs 17.1%); 'drug consumption' (70.8 vs 45.2%); and 'reduced performance in main activity' (60 vs 27.4%). Compared with the general population, the study sample reported significantly worse HR-QOL scores in four dimensions of the SF-36 ('bodily pain', 'vitality', 'social functioning' and 'role-emotional'. Additionally, individuals meeting Rome II criteria reported worse HR-QOL scores than those individuals meeting exclusively Rome I criteria, especially in the 'bodily pain' and 'general health' dimensions.<bold>Conclusions: </bold>The burden of illness in IBS is important and correlated to the diagnostic criteria employed. Individuals who met Rome II criteria reported a higher level of resource utilisation and worse HR-QOL than individuals meeting exclusively Rome I criteria.
- Subjects
IRRITABLE colon; MEDICAL care use
- Publication
PharmacoEconomics, 2002, Vol 20, Issue 11, p749
- ISSN
1170-7690
- Publication type
journal article
- DOI
10.2165/00019053-200220110-00004