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- Title
Long-term exposure to air pollution and severe COVID-19 in Catalonia: a population-based cohort study.
- Authors
Ranzani, Otavio; Alari, Anna; Olmos, Sergio; Milà, Carles; Rico, Alex; Ballester, Joan; Basagaña, Xavier; Chaccour, Carlos; Dadvand, Payam; Duarte-Salles, Talita; Foraster, Maria; Nieuwenhuijsen, Mark; Sunyer, Jordi; Valentín, Antònia; Kogevinas, Manolis; Lazcano, Uxue; Avellaneda-Gómez, Carla; Vivanco, Rosa; Tonne, Cathryn
- Abstract
The association between long-term exposure to ambient air pollutants and severe COVID-19 is uncertain. We followed 4,660,502 adults from the general population in 2020 in Catalonia, Spain. Cox proportional models were fit to evaluate the association between annual averages of PM2.5, NO2, BC, and O3 at each participant's residential address and severe COVID-19. Higher exposure to PM2.5, NO2, and BC was associated with an increased risk of COVID-19 hospitalization, ICU admission, death, and hospital length of stay. An increase of 3.2 µg/m3 of PM2.5 was associated with a 19% (95% CI, 16–21) increase in hospitalizations. An increase of 16.1 µg/m3 of NO2 was associated with a 42% (95% CI, 30–55) increase in ICU admissions. An increase of 0.7 µg/m3 of BC was associated with a 6% (95% CI, 0–13) increase in deaths. O3 was positively associated with severe outcomes when adjusted by NO2. Our study contributes robust evidence that long-term exposure to air pollutants is associated with severe COVID-19. In this study, the authors investigate the relationship between exposure to air pollutants and severe COVID-19 disease using data from a cohort of ~5 million people in Catalonia, Spain. They find that long-term exposure to pollutants is associated with a higher risk of COVID-19-related hospitalization, death, intensive care admission, and length of hospital stay.
- Subjects
CATALONIA (Spain); LENGTH of stay in hospitals; COVID-19; COHORT analysis; AIR pollutants; AIR pollution
- Publication
Nature Communications, 2023, Vol 14, Issue 1, p1
- ISSN
2041-1723
- Publication type
Article
- DOI
10.1038/s41467-023-38469-7