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- Title
Effect of Intermittent Fasting on Cardiometabolic Health in the Chinese Population: A Meta-Analysis of Randomized Controlled Trials.
- Authors
Cheung, Katy; Chan, Vicky; Chan, Stephanie; Wong, Martin Ming Him; Chung, Gary Ka-Ki; Cheng, Wai-Yin; Lo, Kenneth; Zeng, Fangfang
- Abstract
The efficacy of intermittent fasting (IF), as an emerging weight management strategy, in improving cardiometabolic health has been evaluated in various populations, but that among Chinese individuals has not been systematically studied. A comprehensive search on multiple databases was performed to identify eligible randomized controlled trials (RCTs) up to October 2022. The primary outcome was post-intervention weight loss, and secondary outcomes included changes in cardiometabolic indicators. Effect estimates were meta-analyzed using a random-effects model. In total, nine RCTs with 899 Chinese participants were included. Time-restricted eating was the most adopted IF protocol in this study (six out of nine), followed by alternate-day fasting. The IF intervention significantly reduced body weight, body mass index, body fat mass, homeostatic model assessment of insulin resistance, low-density lipoprotein cholesterol, and triglycerides when compared with control groups. However, no statistically significant reductions in waist circumference, total cholesterol, high-density lipoprotein cholesterol, fasting glucose, systolic blood pressure, and diastolic blood pressure were found. To sum up, IF can be a weight management strategy and may improve the cardiometabolic health of Chinese adults, but more long-term trials using different IF strategies are required to generate robust evidence of its efficacy.
- Subjects
CHINA; HEART physiology; REGULATION of body weight; HDL cholesterol; TRIGLYCERIDES; META-analysis; MEDICAL information storage &; retrieval systems; CONFIDENCE intervals; SYSTEMATIC reviews; SYSTOLIC blood pressure; ANTHROPOMETRY; LDL cholesterol; INTERMITTENT fasting; DIASTOLIC blood pressure; QUALITY assurance; DESCRIPTIVE statistics; RESEARCH funding; MEDLINE; INSULIN resistance
- Publication
Nutrients, 2024, Vol 16, Issue 3, p357
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu16030357