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- Title
Mediterranean Diet and NAFLD: What We Know and Questions That Still Need to Be Answered.
- Authors
Plaz Torres, Maria Corina; Aghemo, Alessio; Lleo, Ana; Bodini, Giorgia; Furnari, Manuele; Marabotto, Elisa; Miele, Luca; Giannini, Edoardo G.
- Abstract
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome and is expected to become the leading cause of end-stage liver disease worldwide over the next few decades. In fact, NAFLD encompasses different clinical scenarios, from the simple accumulation of fat (steatosis) to steatohepatitis (NASH), NASH-cirrhosis, and cirrhosis complications. In this context, it is fundamental to pursue strategies aimed at both preventing the disease and reducing the progression of liver fibrosis once liver damage is already initiated. As of today, no pharmacological treatment has been approved for NAFLD/NASH, and the only recommended treatment of proven efficacy are life-style modifications, including diet and physical exercise pointing at weight loss of 5%–7%. Different dietetic approaches have been proposed in this setting, and in this review, we will discuss the evidence regarding the efficacy of the Mediterranean Diet as a treatment for NAFLD. In particular, we will report the effects on liver-related outcomes.
- Subjects
BEHAVIOR modification; DIET; DIETETICS; EXERCISE; FATTY liver; HEALTH behavior; CIRRHOSIS of the liver; WEIGHT loss; TREATMENT effectiveness; DISEASE progression; MEDITERRANEAN diet
- Publication
Nutrients, 2019, Vol 11, Issue 12, p2971
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu11122971