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- Title
Naturalistic study of the use of transcranial magnetic stimulation in the treatment of depressive relapse.
- Authors
Fitzgerald, Paul B.; Benitez, Jessica; de Castella, Anthony R.; Brown, Timothy L.; Daskalakis, Z. Jeff; Kulkarni, Jayashri
- Abstract
Background: The efficacy of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression has been assessed in a number of acute treatment trials during the last 10 years. Little is known about the long-term impact of the treatment on the disorder and its effectiveness when applied for repeated relapses of depression over time. Method: Nineteen patients who had previously responded to rTMS in clinical trials received treatment with rTMS for a total of 30 episodes of depressive relapse. Results: Approximately 10 months elapsed between treatment episodes. The majority of patients achieved a significant improvement in each treatment course with significant improvements achieved in patients treated with both low-frequency right-sided rTMS and high-frequency left-sided rTMS. Conclusions: The study suggests that rTMS may have value in the treatment of episodes of depressive relapse with little reduction in efficacy over time.
- Subjects
TRANSCRANIAL magnetic stimulation; MENTAL depression; DISEASE relapse; THERAPEUTICS; CLINICAL trials
- Publication
Australian & New Zealand Journal of Psychiatry, 2006, Vol 40, Issue 9, p764
- ISSN
0004-8674
- Publication type
Article
- DOI
10.1080/j.1440-1614.2006.01881.x