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- Title
High‐Frequency Ultrasound and Shear Wave Elastography in Quantitative Differential Diagnosis of High‐Risk and Low‐Risk Basal Cell Carcinomas.
- Authors
Liang, Jian‐Feng; Feng, Ming‐Chu; Luo, Ping‐Ping; Guan, Jian‐Ying; Chen, Gao‐Fei; Wu, Shu‐Yi; Wang, Jing; Feng, Mu‐Yin
- Abstract
Objectives: The purpose of this study was to investigate the value of high‐frequency ultrasound and shear wave elastography (SWE) in quantitative differential diagnosis of high‐risk and low‐risk basal cell carcinomas (BCCs). Methods: A total of 52 BCCs confirmed by surgical pathology were studied. Taking pathologic subtypes as reference, all the cases were classified as high‐risk BCCs or low‐risk BCCs. High‐frequency ultrasound parameters and SWE parameters recorded preoperatively were retrospectively analyzed. The differences of two groups were compared. Results: There were 12 high‐risk BCCs and 40 low‐risk BCCs. The maximum infiltration depth (MID) and average Young's modulus (Eave) of high‐risk BCCs were 5.76 ± 2.56 mm and 31.61 ± 12.36 kPa, whereas of low‐risk BCCs were 4.29 ± 1.77 mm and 20.04 ± 4.74 kPa, respectively, P <.05. The area under the receiver operator characteristic curve of MID and Eave were 0.714 and 0.811, P >.05. Taking 5.5 mm of MID and 24.45 kPa of Eave as the threshold for the diagnosis of high‐risk BCCs, the sensitivity, specificity, and accuracy were 58.3%, 82.5%, 76.9% and 75.0%, 82.5%, 80.8%, P >.05. Conclusions: The MID and Eave of the lesion can be used to determine the recurrence risk of BCCs and provide a reference for the development of individualized treatment plans.
- Subjects
BASAL cell carcinoma; SHEAR waves; DIFFERENTIAL diagnosis; MICROBUBBLES; ULTRASONIC imaging; ELASTOGRAPHY
- Publication
Journal of Ultrasound in Medicine, 2022, Vol 41, Issue 6, p1447
- ISSN
0278-4297
- Publication type
Article
- DOI
10.1002/jum.15829