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- Title
Persistent Circulating Severe Acute Respiratory Syndrome Coronavirus 2 Spike Is Associated With Post-acute Coronavirus Disease 2019 Sequelae.
- Authors
Swank, Zoe; Senussi, Yasmeen; Manickas-Hill, Zachary; Yu, Xu G; Li, Jonathan Z; Alter, Galit; Walt, David R
- Abstract
The diagnosis of postacute sequelae of coronavirus disease 2019 (PASC) poses an ongoing medical challenge. To identify biomarkers associated with PASC we analyzed plasma samples collected from PASC and coronavirus disease 2019 patients to quantify viral antigens and inflammatory markers. We detect severe acute respiratory syndrome coronavirus 2 spike predominantly in PASC patients up to 12 months after diagnosis.
- Subjects
VIRAL antigens; DISEASE progression; BIOMARKERS; CYTOKINES; SARS-CoV-2; COVID-19; POST-acute COVID-19 syndrome; CORONAVIRUS spike protein; BLOOD plasma; PHENOTYPES
- Publication
Clinical Infectious Diseases, 2023, Vol 76, Issue 3, pe487
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciac722