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- Title
Antimicrobial Resistance Gene Acquisition and Depletion Following Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection.
- Authors
Leung, Victor; Vincent, Caroline; Edens, Thaddeus J; Miller, Mark; Manges, Amee R
- Abstract
Fecal microbiota transplantation (FMT) may be a novel approach to eliminate multidrug-resistant bacteria from the gut and to prevent future infections. Using whole metagenome sequencing data from 8 FMT donor--recipient pairs, we identifed 37 and 95 antimicrobial resistance genes that were acquired by or removed from FMT recipients, respectively.
- Subjects
CLOSTRIDIUM diseases; DRUG resistance in microorganisms; GENETIC techniques; GENOMES; MULTIDRUG resistance; DISEASE relapse; SEQUENCE analysis
- Publication
Clinical Infectious Diseases, 2018, Vol 66, Issue 3, p456
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/cix821