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- Title
Research Highlights.
- Abstract
The article informs about some new researches in science. Researchers have exploited the nutritional needs of a salmonella strain to target and kill tumor cells. They selected strains of Salmonella typhimurium that are dependent on the presence of the amino acids leucine and arginine for growth. Another research came to the conclusion that induction of CD40-receptor expression in dendritic cells is a key step in their activation of cytotoxic T lymphoctes in epitope-specific immunotherapy. However, endogenous CD40 regulatory mechanisms often lead to transient dendritic cell activation. What is more, systemic, nontargeted CD40 stimulation can produce negative side effects because of the receptor's ubiquitous expression on many cell types. Another research concluded that carbohydrate-cell interactions are ubiquitous in nature and figure in numerous developmental and pathogenic events.
- Subjects
SCIENCE news briefs; SCIENTIFIC experimentation; SALMONELLA; AMINO acids; DENDRITIC cells; ORGANIC acids; LABORATORIES; SCIENTISTS; RESEARCH
- Publication
Nature Biotechnology, 2005, Vol 23, Issue 2, p189
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt0205-189