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- Title
Integrated nanoliter systems.
- Authors
Jong Wook Hong, George M.; Quake, Stephen R.
- Abstract
Microfluidic chip platforms for manipulating liquid volumes in the nanoliter range are slowly inching their way into mainstream genomic and proteomic research. The principal challenge faced by these technologies is the need for high-throughput processing of increasingly smaller volumes, with ever higher degrees of parallelization. Significant advances have been made over the past few years in addressing these needs through electrokinetic manipulation, vesicle encapsulation and mechanical valve approaches. These strategies allow levels of integration density and platform complexity that promise to make them into serious alternatives to current robotic systems.
- Subjects
NANOTECHNOLOGY; BIOTECHNOLOGY; FLUIDS
- Publication
Nature Biotechnology, 2003, Vol 21, Issue 10, p1179
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt871