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- Title
Reduction in the incidence of awareness using BIS monitoring.
- Authors
Ekman, A.; Lindholm, M.-L.; Lennmarken, C.; Sandin, R.
- Abstract
<bold>Background: </bold>Explicit recall (ER) is evident in approximately 0.2% of patients given general anaesthesia including muscle relaxants. This prospective study was performed to evaluate if cerebral monitoring using BIS to guide the conduction of anaesthesia could reduce this incidence significantly.<bold>Patients and Methods: </bold>A prospective cohort of 4945 consecutive surgical patients requiring muscle relaxants and/or intubation were monitored with BIS and subsequently interviewed for ER on three occasions. BIS values between 40 and 60 were recommended. The results from the BIS-monitored group of patients was compared with a historical group of 7826 similar cases in a previous study when no cerebral monitoring was used.<bold>Results: </bold>Two patients in the BIS-monitored group, 0.04%, had ER as compared with 0.18% in the control group (P < 0.038). Both BIS-monitored patients with ER were aware during intubation when they had high BIS values (> 60) for 4 min and more than 10 min, respectively. However, periods with high BIS = 4 min were also evident in other patients with no ER. Episodes with high BIS, 4 min or more, were found in 19% of the monitored patients during induction, and in 8% of cases during maintenance.<bold>Conclusions: </bold>The use of BIS monitoring during general anaesthesia requiring endotracheal intubation and/or muscle relaxants was associated with a significantly reduced incidence of awareness as compared with a historical control population.
- Subjects
ANESTHESIA; SURGERY; ANESTHESIOLOGY
- Publication
Acta Anaesthesiologica Scandinavica, 2004, Vol 48, Issue 1, p20
- ISSN
0001-5172
- Publication type
journal article
- DOI
10.1111/j.1399-6576.2004.00260.x