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- Title
Clinical Evaluation of Severe Acute Respiratory Syndrome Coronavirus 2 Rapid Antigen Tests During the Omicron Wave in South Africa.
- Authors
Samsunder, Natasha; Vos, Margaretha de; Ngcapu, Sinaye; Giandhari, Jennifer; Lewis, Lara; Kharsany, Ayesha B M; Cawood, Cherie; Oliveira, Tulio de; Karim, Quarraisha Abdool; Karim, Salim Abdool; Naidoo, Kogieleum; Escadafal, Camille; Sivro, Aida; de Vos, Margaretha; Kharsany, Ayesha Bm; Carwood, Cherie; de Olveira, Tulio; de Oliveira, Tulio
- Abstract
We evaluated the performance of nasal and nasopharyngeal Standard Q COVID-19 [coronavirus disease 2019] Ag tests (SD Biosensor) and the Panbio COVID-19 Ag Rapid Test Device (nasal; Abbott) against the Abbott RealTime severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) assay during the Omicron (clades 21M, 21K, and 21L) wave in South Africa. Overall, all evaluated tests performed well, with high sensitivity (range, 77.78%-81.42%) and excellent specificity values (>99%). The sensitivity of rapid antigen tests increased above 90% in samples with cycle threshold <20, and all 3 tests performed best within the first week after symptom onset.
- Publication
Journal of Infectious Diseases, 2022, Vol 226, Issue 8, p1412
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1093/infdis/jiac333