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- Title
Pediatric Pituitary Adenoma: A study of 12 cases.
- Authors
Dua, Rakesh K.; Abraham, R. G.; Pandey, P.; Vasudevan, S. P.; Balasubramaniam, A.; Devi, B. I.; S., Sampath; Chandramouli, B. A.
- Abstract
INTRODUCTION: Pituitary adenomas occur rarely during childhood. It constitutes less than 3% of supratentorial tumors in children. Most pituitary tumors in children are functional. In children, non functional pituitary tumors account for only 3 to 6%. Children do not often complain of visual symptoms, hence presenting symptoms of these tumors are generally related to endocrine dysfunction, such as growth delay and primary amenorrhea. Prolactinomas are the most frequent pituitary tumors in children. MATERIALS AND METHODS: This was a retrospective study. Data was obtained from case records and patient, correspondence- Between 2001 and 2007, 12 cases of pituitary adenoma were treated at our Institute. RESULTS: There were 7 females and 5 males. All patients were between 14 and 18 years of age. All 7 female patients had secondary amenorrhea. 6 patients had visual impairment. 5 patients had prolactin, 2 growth hormone, 2 adrenocortitrophic hormone (ACTH) and 1 thyroid stimulating hormone (TSH) secreting pituitary adenomas. Craniopharyngioma was considered the pre operative diagnosis in 4 and thalamic glioma in 1 patient. 5 patients underwent craniotomy, 6 patients underwent sub labial transsphenoidal surgery and 1 patient had craniotomy following a transsphenoidal approach. Of patients who underwent transcranial surgery 2 had deterioration of vision, 1 developed a third nerve palsy and 2 developed diabetes insipidus. 3 patients who underwent transsphenoidal surgery had diabetes insipid us following surgery. There was no mortality amongst these patients. Of the 6-patients who had residual tumors following surgery, three prolactin secreting tumor patients were started on Bromocriptine and 3 were referred for post operative radiotherapy. CONCLUSION: The majority of the pituitary tumors in children are functioning adenomas. This differential diagnosis should be considered in children with sellar/ suprasellar tumors and hormonal assays should be performed. Sublabial transsphenoidal approach is a safe and effective surgical modality for these tumors and should be the procedure of choice.
- Subjects
PITUITARY tumors; TUMORS in children; ADENOMA; AMENORRHEA; TUMORS
- Publication
Journal of Pediatric Neurosciences, 2007, Vol 2, Issue 2, p100
- ISSN
1817-1745
- Publication type
Article