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- Title
Elevated prostate-specific antigen in Paget's disease.
- Authors
Solav, Shrikant Vasantrao; Inamdar, Manohar; Savale, Shailendra V.
- Abstract
A 70-year-old man diagnosed with acinar adenocarcinoma prostate (Gleason score 4 + 4 = 8) underwent bone scintigraphy due to high serum prostate-specific antigen level (224 ng/mL; normal <4 ng/mL). Bone scan revealed moderately increased diffuse tracer uptake in the right hemipelvis, while the rest of the scan appeared normal, leading to suspicion of Paget's disease. Gallium-68-prostate-specific membrane antigen (PSMA) positron emission tomography--computed tomography scan (CT) showed a PSMA-avid lesion in the left lobe of the prostate, with no PSMA uptake in the areas of diffuse sclerosis in the right hemipelvis, as seen on CT. This confirmed the diagnosis of Paget's disease.
- Subjects
RADIOISOTOPE therapy; GALLIUM isotopes; PROSTATE-specific antigen; PELVIC bones; COMPUTED tomography; POSITRON emission tomography; PROSTATE tumors; ANTIGENS; PROSTATE-specific membrane antigen; OSTEITIS deformans; RADIONUCLIDE imaging
- Publication
Indian Journal of Urology, 2023, Vol 39, Issue 4, p328
- ISSN
0970-1591
- Publication type
Article
- DOI
10.4103/iju.iju_218_23