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- Title
High Glucose via Peroxynitrite Causes Tyrosine Nitration and Inactivation of Prostacyclin Synthase That Is Associated With Thromboxane/Prostaglandin H[sub2] Receptor-Mediated Apoptosis and Adhesion Molecule Expression in Cultured Human Aortic...
- Authors
Ming-Hui Zou; Chaomei Shi; Cohen, Richard A.
- Abstract
Investigates the influence of high glucose exposure of cultured human aortic endothelial cells on the release of superoxide anion and production of peroxynitrite. Importance of prostacyclin synthase in development of diabetic endothelial dysfunction; Factors affecting the occurrence of diabetic vascular illness; Causes of death in diabetics.
- Subjects
VASCULAR endothelium; GLUCOSE; SUPEROXIDES; CYTOLOGY; PHYSIOLOGY
- Publication
Diabetes, 2002, Vol 51, Issue 1, p198
- ISSN
0012-1797
- Publication type
Article
- DOI
10.2337/diabetes.51.1.198