We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Alveolar Vascular Remodeling in Nonspecific Interstitial Pneumonia: Replacement of Normal Lung Capillaries with COL15A1-Positive Endothelial Cells.
- Authors
Schupp, Jonas C.; Manning, Edward P.; Chioccioli, Maurizio; Kamp, Jan C.; Christian, Leonard; Changwan Ryu; Herzog, Erica; Kühnel, Mark P.; Prasse, Antje; Kaminski, Naftali; Jonigk, Danny D.; Homer, Robert J.
- Abstract
The article explores vascular changes in nonspecific interstitial pneumonia (NSIP), a lung disease. It reveals a significant replacement of normal lung capillaries with COL15A1-positive endothelial cells in NSIP patients, potentially affecting gas exchange and lung permeability. It further underscores the need for further research on the role of COL15A1 in lung fibrosis and its implications for fibrotic lung diseases.
- Subjects
PULMONARY fibrosis; VASCULAR remodeling; ENDOTHELIAL cells; LUNGS; CAPILLARIES
- Publication
American Journal of Respiratory & Critical Care Medicine, 2023, Vol 208, Issue 7, p819
- ISSN
1073-449X
- Publication type
Article
- DOI
10.1164/rccm.202303-0544LE