We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Antiphospholipid syndrome and lupus anticoagulant-hypoprothrombinemia.
- Authors
Peralta-Amaro, A L; Triana-González, S; Manzo-Carballo, M F; Lastra, O L Vera; García-Chávez, J; Lucas-Hernández, A
- Abstract
Google Scholar Crossref Search ADS PubMed WorldCat 2 Sreedharanunni S, Ahluwalia J, Kumar N, Bose SK, Dhawan R, Malhotra P. Lupus anticoagulant-hypoprothrombinemia syndrome: a rare cause of intracranial bleeding. Learning points for clinicians Although lupus anticoagulant-hypoprothrombinemia syndrome is a rare cause of bleeding in patients with antiphospholipid syndrome, clinicians should always have it in mind to initiate treatment as soon as possible. Introduction Antiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombosis; hemorrhagic events can occur in about 10%.[1],[2] One of the causes of bleeding in APS, is the lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS), an extremely rare entity that depends on the presence of non-neutralizing antibodies against coagulation factor II (FII).[3] We present the case of a patient with APS and LAHPS that presented intracranial hemorrhage, treated with Factor Eight Inhibitor Bypassing Activity (FEIBA).
- Subjects
ANTIPHOSPHOLIPID syndrome; INTRACRANIAL hemorrhage; BLOOD coagulation factors
- Publication
QJM: An International Journal of Medicine, 2023, Vol 116, Issue 4, p308
- ISSN
1460-2725
- Publication type
Article
- DOI
10.1093/qjmed/hcac243