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- Title
Disseminated gestational choriocarcinoma presenting with hepatic and uveal metastases, hook effect, and choriocarcinoma syndrome.
- Authors
Aswani, Yashant; Thakkar, Hemangini; Hira, Priya
- Abstract
Choriocarcinoma is a human chorionic gonadotrophin (HCG)-secreting tumor that comprises vascular channels. It has a tendency for widespread metastasis, common sites for which include the lung, vagina, brain, liver, bone, intestine, and kidney. We describe a 30-year-old female who presented with hepatitis-like features and bilateral diminution of vision, and subsequently developed hemothorax and hemoperitoneum--all rare and seemingly unrelated manifestations which were Anally attributable to metastases from gestational choriocarcinoma. To further complicate the clinical scenario, the serum HCG of the patient was mildly raised (due to a phenomenon called hook effect). Subsequently, the patient developed disseminated intravascular coagulation and succumbed to her illness. In this report, we discuss the imaging findings of choriocarcinoma, its potential sites of metastases, and the hook effect.
- Publication
Indian Journal of Radiology & Imaging, 2016, Vol 26, Issue 4, p482
- ISSN
0971-3026
- Publication type
Article
- DOI
10.4103/0971-3026.195781