The author reflects on the neurological aspects of Chikungunya virus (CHIKV). He notes that CHIKV is an insect-borne virus belonging to the Alphavirus and the family Togaviridae that is transmitted to humans by virus-carrying Aedes mosquitoes and was first recognized in epidemic form in East Africa from 1952 to 1953. He adds that infection from CHIKV infection typically induces a mild disease in humans, characterized by fever, myalgia, arthralgia, and rash.