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- Title
A Short-term Open Trial of Clomipramine in the Treatment of Patients with Panic Attacks.
- Authors
Judd, F. K.; Burrows, G. D.; Marriott, P. F.; Farrott, P.; Blair-West, S.; Norman, T. R.
- Abstract
Clomipramine was used to treat 14 patients with panic attacks. Diagnosis was made according Lo DSM-III criteria for agoraphobia with panic attacks or panic disorder uncomplicated. An open evaluation of the drug over an 8-week treatment period was conducted. A total of 10 patients completed the study. Clomipramine was effective in reducing the mean number of panic attacks, the greatest response being observed in the first 2 weeks of treatment. Findings on all outcome measures showed that clomipramine was also effective in alleviating depression secondary to panic attacks, non-specific aspects of anxiety and improving phobic avoidance. There was a suggestion that responders to treatment received tower doses of clomipramine than non-responders. Further studies are required to evaluate this issue and the role of clomipramine in the treatment or panic disorders.
- Subjects
PANIC disorders; HEALTH outcome assessment; ANXIETY; PHOBIAS; MENTAL depression; DEPRESSED persons
- Publication
Human Psychopharmacology: Clinical & Experimental, 1991, Vol 6, Issue 1, p53
- ISSN
0885-6222
- Publication type
Article
- DOI
10.1002/hup.470060110