We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Molecular characteristics of the Taiwanese multiple drug-resistant ST59 clone of Panton-Valentine leucocidin-positive community-acquired methicillin-resistant Staphylococcus aureus from pediatric cellulitis.
- Authors
Higuchi, Wataru; Wei-Chun Hung; Takano, Tomomi; Iwao, Yasuhisa; Ozaki, Kyoko; Isobe, Hirokazu; Lee-Jene Teng; Shimazaki, Tetsuya; Honda, Akihito; Higashide, Masato; Hanaki, Hideaki; Yamamoto, Tatsuo
- Abstract
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), which often produces Panton-Valentine leucocidin (PVL), has emerged worldwide as a life-threatening pathogen. Herein, we describe molecular characteristics of MRSA isolated from abdominal cellulitis in a 7-year-old Japanese boy. This MRSA was PVL-positive and belonged to the Taiwanese multiple drug-resistant CA-MRSA clone with the genotype of ST59, staphylococcal cassette chromosome mec (SCC mec) VII (SCC mecV, according to recent reclassification), agr1a (a novel agr1 subtype), and SaPI (which carried seb1, a newly designated variant seb gene). This study demonstrates the first isolation of the Taiwanese PVL-positive ST59 MRSA clone in Japan. The data also demonstrate novel subtypes in agr1 and seb and suggest that a combination of agr1a, seb1, and PVL could contribute to cellulitis (and its recurrence). Recently, a variety of PVL-positive MRSA clones are accumulating in Japan.
- Subjects
TAIWAN; DRUG resistance in microorganisms; METHICILLIN-resistant staphylococcus aureus; CELLULITIS; PEDIATRICS
- Publication
Journal of Infection & Chemotherapy (Springer Science & Business Media B.V.), 2010, Vol 16, Issue 2, p144
- ISSN
1341-321X
- Publication type
Article
- DOI
10.1007/s10156-010-0029-9