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- Title
Phenolic Compounds' Occurrence in Opuntia Species and Their Role in the Inflammatory Process: A Review.
- Authors
Zeghbib, Walid; Boudjouan, Fares; Vasconcelos, Vitor; Lopes, Graciliana
- Abstract
Within the Cactaceae family, Opuntia comprises the most widespread species, with a recognized importance in human life, including feeding, domestic use as home natural barriers, and as a traditional remedy for diverse diseases and conditions such asthma, edema, and burns. Indeed, scientific reports have stated that these health benefits may be due to various active compounds, particularly polyphenols, which are ubiquitously found in plants and have proven their pharmacological efficiency by displaying antimicrobial, anti-cancer, and anti-inflammatory activities, among others. Opuntia species contain different classes of phenolic compounds that are recognized for their anti-inflammatory potential. Among them, quercetin, isorhamnetin, and kaempferol derivates were reported to greatly contribute to modulate cells' infiltration and secretion of soluble inflammatory mediators, with key implications in the inflammatory process. In this review, we make a summary of the different classes of phenolic compounds reported in Opuntia species so far and explore their implications in the inflammatory process, reported by in vitro and in vivo bioassays, supporting the use of cactus in folk medicine and valorizing them from the socio-economic point of view.
- Subjects
PHENOLS; OPUNTIA; INFLAMMATION; FLAVONOLS; SPECIES; INFLAMMATORY mediators; PLANT polyphenols
- Publication
Molecules, 2022, Vol 27, Issue 15, p4763
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules27154763