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- Title
Synthesis,Structure and Antifungal Activity of New 3-[(5-Aryl-1,3,4-oxadiazol-2-yl)methyl]benzo[d]thiazol-2(3H)-ones.
- Authors
Jian-Quan Weng; Xing-Hai Liu; Hua Huang; Cheng-Xia Tan; Jie Chen
- Abstract
A series of new 3-[(5-aryl-1,3,4-oxadiazol-2-yl)methy])benzo[d]thiazol-2(3H)-ones were synthesized by reaction of (5-substituted-2-oxobenzothiazolin-3-yl)-acetohydrazide with various aromatic acids in POCl3 under reflux conditions. The structures of the title compounds were confirmed by 1H-NMR, 13C-NMR, IR, MS and elemental analysis. Furthermore, the structure of compound 4i was determined by single-crystal X-ray diffraction. The preliminary bioassy results indicated that some of them showed moderate inhibition activity against Colletotrichum orbiculare, Botrytis cinerea and Rhizoctonia solani.
- Subjects
BOTRYOTINIA; RHIZOCTONIA solani; BOTRYTIS cinerea; AGONOMYCETACEAE; CORTICIUM sasakii
- Publication
Molecules, 2012, Vol 17, Issue 1, p989
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules17010989