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- Title
Morphofunctional Properties of Spindle-Shaped Platelets.
- Authors
Makarov, M. S.
- Abstract
Morphofunctional properties of spindle-shaped platelets under normal and pathological conditions were studied by the method based on vital staining. In donor blood and plasma isolated by centrifugation at 300g, no spindle-shaped platelets were detected; after centrifugation at 3000g, spindle-shaped platelets were detected in a small amount in 20% samples. During plasma storage at 20-22°C, spindle-shaped platelets appeared after 1-2 days, after 3 days their number increased to 30% and higher. Spindle-shaped platelets contained a small number of granules and did not exhibit active adhesion, while the structure of their membranes was normal after 1-2 days of storage and abnormalities appeared during subsequent storage. Spindle-shaped platelets were found in the blood of patients with acute exogenous poisoning and severe thermal trauma. Spindle-shaped platelets can be used as an additional criterion for assessing the quality of the platelet population.
- Subjects
BLOOD platelets; BLOOD plasma; BLOOD donors
- Publication
Bulletin of Experimental Biology & Medicine, 2023, Vol 174, Issue 5, p681
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-023-05769-3