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- Title
Reduced Counts of Various Subsets of Peripheral Blood T Lymphocytes in Patients with Severe Course of COVID-19.
- Authors
Zhao, C.; Hu, X.; Xue, Q.; Chen, L.
- Abstract
This study was intended to define T lymphocyte subsets in different clinical groups of COVID-19-infected patients to explore the interaction between T cell-mediated immune response and the severity of COVID-19 course. Lymphopenia in patients with severe COVID-19 was found. In patients with severe COVID-19 course, the absolute counts of CD3+, CD4+, and CD8+ T lymphocytes at admission were lower than on day 14 after discharge. Further analysis showed that the older were the patients with COVID-19, the more likely they developed severe infection. The results confirmed the significance of T lymphocytes in the clearance of the COVID-19.
- Subjects
T cells; COVID-19; LYMPHOCYTE subsets; OLDER patients; LYMPHOPENIA
- Publication
Bulletin of Experimental Biology & Medicine, 2022, Vol 172, Issue 6, p721
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-022-05464-9