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- Title
Inorganic polyphosphates are important for cell survival and motility of human skin keratinocytes.
- Authors
Simbulan‐Rosenthal, Cynthia M.; Gaur, Anirudh; Sanabria, Virginia A.; Dussan, Lucia J.; Saxena, Rahul; Schmidt, Jozef; Kitani, Takashi; Chen, You‐shin; Rahim, Said; Uren, Aykut; Crooke, Elliott; Rosenthal, Dean S.
- Abstract
The article discusses research which investigated role of inorganic polyphosphate (polyP) in human epidermal cell survival, motility, and proliferation. Topics explored include the observed response of human skin keratinocytes to ultraviolet B (UVB) exposure or wounding, the measurement of intracellular Saccharomyces cerevisiae exopolyphosphatase 1 (ScPPX1) activity, and the contribution of extracellular polyP to the acceleration of wound healing.
- Subjects
INORGANIC polyphosphates; CELL motility; CELL proliferation; KERATINOCYTES; PHYSIOLOGICAL effects of ultraviolet radiation; EXOPOLYPHOSPHATASE; WOUND healing
- Publication
Experimental Dermatology, 2015, Vol 24, Issue 8, p636
- ISSN
0906-6705
- Publication type
Article
- DOI
10.1111/exd.12729