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- Title
Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264.
- Authors
Steenkamp, Devin W.; Cacicedo, Jose M.; Sullivan, Catherine A.
- Abstract
The authors comment on a 2019 article by Sims et al on the occurrence of proinsulin (PI) secretion on type 1 diabetic individuals even without measurable serum C-peptide. They observe differences in PI concentrations as per assay used, and state that the study samples be reassayed with the use of validated PI kits. Also noted is the importance of the assay chose for PI measurement for accurate determination of concentrations.
- Subjects
TYPE 1 diabetes; SECRETION; PROINSULIN; DIABETES
- Publication
Diabetes Care, 2019, Vol 42, Issue 5, pe84
- ISSN
0149-5992
- Publication type
letter
- DOI
10.2337/dc19-0158