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- Title
The relevance of MRI findings in joints of persons with haemophilia: Insights from the last decade.
- Authors
Foppen, Wouter; van Leeuwen, Flora H. P.; Timmer, Merel A.; Fischer, Kathelijn
- Abstract
This article discusses the relevance of magnetic resonance imaging (MRI) findings in individuals with haemophilia. It highlights that most bleeding episodes in haemophilia occur in the large synovial joints, leading to irreversible haemophilic arthropathy. The article emphasizes the importance of detecting subclinical bleeding and inflammation, as they contribute to the development of arthropathy. MRI is considered the gold standard for evaluating early blood-induced joint changes in haemophilia, and the International Prophylaxis Study Group (IPSG) has developed a comprehensive scoring scheme for MRI assessment. The article also discusses the clinical consequences of subclinical bleeding, the evaluation of joint effusions, and the assessment of osteochondral abnormalities using MRI. It concludes by stating that MRI provides a complete overview of joint status in individuals with haemophilia and that the IPSG MRI Scale version 2.0 facilitates standardized MRI scoring for future outcome studies.
- Subjects
HEMOPHILIACS; MAGNETIC resonance imaging; OSTEOCHONDRITIS; TEENAGERS
- Publication
Haemophilia, 2024, Vol 30, Issue 4, p877
- ISSN
1351-8216
- Publication type
Article
- DOI
10.1111/hae.15058