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- Title
Tolvaptan Response in a Hyponatremic Newborn with Syndrome of Inappropriate Secretion of Antidiuretic Hormone.
- Authors
Zeybek, Cengiz; Bozat, Ali Dinç; Calisici, Erhan; Bolat, Ahmet; Saygili Karagol, Belma
- Abstract
The use of tolvaptan to treat both euvolemic and hypervolemic hyponatremia has rapidly increased in recent years. However, data on its effects on children, especially newborns and infants, are limited. Here, we present a newborn who developed syndrome of inappropriate secretion of antidiuretic hormone following an intracranial hematoma drainage operation who was unresponsive to conventional treatments. The infant was successfully treated with tolvaptan, a competitive inhibitor of the vasopressin V2 receptor.
- Subjects
INAPPROPRIATE ADH syndrome; NEWBORN infants; INFANTS; INTRACRANIAL hematoma; TREATMENT effectiveness
- Publication
Case Reports in Pediatrics, 2021, p1
- ISSN
2090-6803
- Publication type
Article
- DOI
10.1155/2021/9920817