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- Title
An Extended Release Multi-particulate Drug Delivery System for Oral use.
- Authors
Kumar, Prevesh; Sharma, Aditya; Rastogi, Vaibhav
- Abstract
Therapeutic research and development are increasingly focusing on delivery systems which enhance desirable objectives while minimizing side effects. Nowadays Dose dumping is a major problem of single particulate dosage forms. So there is a need of extended release Multi-particulate drug delivery systems (MDDS). Production of pellet offers flexibility in dosage form design and development with an active ingredient are administered in the form of capsule. MDDS are mostly used for oral route, which consist of multiplicity of small discrete units and each exhibit different characteristics. It based on subunits such as granules, beads, micro spheres, pellets, spheroids and Minitab, which shows various benefits over monolithic devices. This present review outlines the transient account of all important manufacturing and evaluation technique for MDDS. The manufacturing techniques have been deliberated.MDDS consist of multiplicity of small discrete units that exhibit different characteristicsand is based on subunits such as granules, beads, microspheres, pellets, spheroids andMinitab. The pharmaceutical scientists have achieved a great success in developing most therapeutic systems with suitable natural polymer. The current study focuses on the advantages, limitations, types and pharmaceutical application of MDDS.
- Subjects
DRUG delivery systems; PHARMACEUTICAL technology; DRUG side effects; BIOPOLYMERS; DRUG dosage
- Publication
International Journal of Pharmacy & Life Sciences, 2019, Vol 10, Issue 6, p85
- ISSN
0976-7126
- Publication type
Article