We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Decreased Cortical Thickness in the Anterior Cingulate Cortex in Adults with Autism.
- Authors
Boisgontier, Jennifer; Laidi, Charles; Hotier, Sevan; d'Albis, Marc-Antoine; Houenou, Josselin; Gaman, Alexandru; Scheid, Isabelle; Leboyer, Marion; Toledano, Elie; Ly-Le Moal, Myriam; Delorme, Richard; de Pierrefeu, Amicie; Duchesnay, Edouard; Petit, Julie; Bolognani, Federico; Czech, Christian; Bouquet, Céline; Holiga, Štefan; Dukart, Juergen; Amestoy, Anouck
- Abstract
Autism spectrum disorder (ASD) is a developmental disorder underdiagnosed in adults. To date, no consistent evidence of alterations in brain structure has been reported in adults with ASD and few studies were conducted at that age. We analyzed structural magnetic resonance imaging data from 167 high functioning adults with ASD and 195 controls. We ran our analyses on a discovery (n = 301) and a replication sample (n = 61). The right caudal anterior cingulate cortical thickness was significantly thinner in adults with ASD compared to controls in both the discovery and the replication sample. Our work underlines the relevance of studying the brain anatomy of an adult ASD population.
- Subjects
DIAGNOSIS of autism; LIMBIC system; MAGNETIC resonance imaging; PEOPLE with disabilities; ADULTS
- Publication
Journal of Autism & Developmental Disorders, 2019, Vol 49, Issue 4, p1402
- ISSN
0162-3257
- Publication type
Article
- DOI
10.1007/s10803-018-3807-3