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- Title
The effects of hypo- and hypercaloric dietary intervention on mechanical ventilation and length of stay in ICU and hospital in critically ill patients.
- Authors
Tarighat-Esfanjani, Faezeh; Ghalichi, Faezeh; Zadeh, Meysam Zare; Tarighat-Esfanjani, Ali
- Abstract
Background: Nutritional therapeutic goals for critically ill patients should be considered for minimizing the potential for malnutrition and reducing the catastrophic outcomes of critical illness. A systematic review and meta-analysis was conducted in order to assess the effect of hypocaloric and hypercaloric diet on outcomes of critical illness. Materials and Methods: PubMed-Medline, SCOPUS, Web of Science and Embase databases and Google Scholar were searched up to December 2021. Random- and fixed-effects analysis was used to perform meta-analysis. Subgroup analyses were carried out to express the results across various subgroups. Begg's test was performed to detect publication bias. Quality assessment was performed using Cochrane Collaboration's tool. Results: A total of 12 studies were included in meta-analysis. Hyper-caloric diet had no significant effect on days of intensive care unit (ICU) (WMD = 0.95days; 95% CI: -0.41, 2.30; P= 0.172) and duration of mechanical ventilation (MV) (WMD = 0.71days; 95% CI: -1.53, 2.94; P= 0.535), but significantly enhanced hospital length of stay (HLOS) (WMD = 391 days; 95% CI: 2.18, 5.65; P<0.001). Hypo-caloric diet significantly decreased duration of MV (SMD = -1.07 days; 95% CI: -1.97, - 0.17; P= 0.006) and HLOS (WMD = -2.93 days; 95% CI: -5.47, -0.40; P= 0.023). However, it had no effect on days in ICU (WMD = -0.16 days; 95% CI: -1.18, 0.86; P= 0.754). Conclusion: The results of the present metaanalysis indicate that hypocaloric dietary approach has beneficial impacts on the recovery of critically ill patients in comparison with iso- and hypercaloric interventions.
- Subjects
CRITICALLY ill; ARTIFICIAL respiration; INTENSIVE care units; PUBMED (Online service); PATIENTS' attitudes
- Publication
Journal of Nutrition, Fasting & Health, 2022, Vol 10, p131
- ISSN
2821-2746
- Publication type
Article