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Tubulin and Tubulin Posttranslational Modifications in Alzheimer's Disease and Vascular Dementia.
- Published in:
- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.730107
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- Publication type:
- Article
Esculetin Provides Neuroprotection against Mutant Huntingtin-Induced Toxicity in Huntington's Disease Models.
- Published in:
- Pharmaceuticals (14248247), 2021, v. 14, n. 10, p. 1044, doi. 10.3390/ph14101044
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- Publication type:
- Article
Mutant huntingtin impairs immune cell migration in Huntington disease.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 12, p. 4737, doi. 10.1172/JCI64484
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- Publication type:
- Article
DJ-1 in Parkinson's Disease: Clinical Insights and Therapeutic Perspectives.
- Published in:
- Journal of Clinical Medicine, 2019, v. 8, n. 9, p. 1377, doi. 10.3390/jcm8091377
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- Publication type:
- Article
Drosophila Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity.
- Published in:
- Frontiers in Molecular Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnmol.2019.00086
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- Publication type:
- Article
Glutathione peroxidase activity is neuroprotective in models of Huntington's disease.
- Published in:
- Nature Genetics, 2013, v. 45, n. 10, p. 1249, doi. 10.1038/ng.2732
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- Publication type:
- Article
A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease.
- Published in:
- Nature Genetics, 2005, v. 37, n. 5, p. 526, doi. 10.1038/ng1542
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- Publication type:
- Article
A Drosophila RNAi collection is subject to dominant phenotypic effects.
- Published in:
- Nature Methods, 2014, v. 11, n. 3, p. 222, doi. 10.1038/nmeth.2856
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- Publication type:
- Article
Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.
- Published in:
- PLoS Biology, 2018, v. 16, n. 4, p. 1, doi. 10.1371/journal.pbio.2003611
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- Publication type:
- Article
Glycation potentiates neurodegeneration in models of Huntington's disease.
- Published in:
- Scientific Reports, 2016, p. 36798, doi. 10.1038/srep36798
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- Publication type:
- Article
Yeast as a model for studying human neurodegenerative disorders.
- Published in:
- Biotechnology Journal, 2008, v. 3, n. 3, p. 325, doi. 10.1002/biot.200700217
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- Publication type:
- Article
Yeast as a model for studying human neurodegenerative disorders.
- Published in:
- Biotechnology Journal, 2008, v. 3, n. 3, p. 421, doi. 10.1002/biot.421
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- Publication type:
- Article
Yeast as a drug discovery platform in Huntington's and Parkinson's diseases.
- Published in:
- Biotechnology Journal, 2006, v. 1, n. 3, p. 258, doi. 10.1002/biot.200500043
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- Publication type:
- Article
Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease.
- Published in:
- Journal of Neurochemistry, 2021, v. 158, n. 2, p. 539, doi. 10.1111/jnc.15360
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- Publication type:
- Article
Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease.
- Published in:
- Journal of Neurochemistry, 2021, v. 158, n. 1, p. 539, doi. 10.1111/jnc.15360
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- Publication type:
- Article
A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics.
- Published in:
- PLoS Genetics, 2020, v. 16, n. 11, p. 1, doi. 10.1371/journal.pgen.1009129
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- Publication type:
- Article
Publisher Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06888-6
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- Publication type:
- Article
Loss of Hsp70 Exacerbates Pathogenesis But Not Levels of Fibrillar Aggregates in a Mouse Model of Huntington's Disease.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 28, p. 9104, doi. 10.1523/JNEUROSCI.2250-09.2009
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- Publication type:
- Article
AggregationProne Proteins Modulate Huntingtin Inclusion Body Formation in Yeast.
- Published in:
- PLoS Currents, 2014, p. 23, doi. 10.1371/currents.hd.501008f3051342c9a5c0cd0f3a5bf3a4
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- Publication type:
- Article
RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies.
- Published in:
- Brain Pathology, 2021, v. 31, n. 1, p. 120, doi. 10.1111/bpa.12890
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- Publication type:
- Article
Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma.
- Published in:
- Antioxidants, 2022, v. 11, n. 2, p. 315, doi. 10.3390/antiox11020315
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- Publication type:
- Article
Ablation of kynurenine 3-monooxygenase rescues plasma inflammatory cytokine levels in the R6/2 mouse model of Huntington's disease.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-84858-7
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- Publication type:
- Article
Protein phosphatase 1 regulates huntingtin exon 1 aggregation and toxicity.
- Published in:
- Human Molecular Genetics, 2017, v. 26, n. 19, p. 3763, doi. 10.1093/hmg/ddx260
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- Publication type:
- Article
Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 4, p. 1077, doi. 10.1093/hmg/ddu521
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- Publication type:
- Article
The small GTPase Rab11 co-localizes with α-synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 25, p. 6732, doi. 10.1093/hmg/ddu391
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- Publication type:
- Article
Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's disease.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 12, p. 3129
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- Publication type:
- Article
DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 3, p. 755, doi. 10.1093/hmg/ddt466
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- Publication type:
- Article
The small GTPase Rab11 co-localizes with α-synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity.
- Published in:
- Human Molecular Genetics, 2012, v. 21, n. 25, p. 1, doi. 10.1093/hmg/ddu391
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- Publication type:
- Article
Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease.
- Published in:
- Human Molecular Genetics, 2012, v. 21, n. 13, p. 2912, doi. 10.1093/hmg/dds117
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- Publication type:
- Article
Choosing and using Drosophila models to characterize modifiers of Huntington's disease.
- Published in:
- Biochemical Society Transactions, 2012, v. 40, n. 4, p. 739, doi. 10.1042/BST20120072
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- Publication type:
- Article
Dysfunction of RAB39B‐Mediated Vesicular Trafficking in Lewy Body Diseases.
- Published in:
- Movement Disorders, 2021, v. 36, n. 8, p. 1744, doi. 10.1002/mds.28605
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- Publication type:
- Article
Structural basis of kynurenine 3-monooxygenase inhibition.
- Published in:
- Nature, 2013, v. 496, n. 7445, p. 382, doi. 10.1038/nature12039
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- Publication type:
- Article
A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.
- Published in:
- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0520-5
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- Publication type:
- Article
Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane.
- Published in:
- Biomedicines, 2022, v. 10, n. 9, p. 2294, doi. 10.3390/biomedicines10092294
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- Publication type:
- Article
Therapeutic Targeting of Rab GTPases: Relevance for Alzheimer's Disease.
- Published in:
- Biomedicines, 2022, v. 10, n. 5, p. 1141, doi. 10.3390/biomedicines10051141
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- Publication type:
- Article
Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05653-z
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- Publication type:
- Article
A Novel Sit4 Phosphatase Complex Is Involved in the Response to Ceramide Stress in Yeast.
- Published in:
- Oxidative Medicine & Cellular Longevity, 2013, v. 2013, p. 1, doi. 10.1155/2013/129645
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- Publication type:
- Article
The Amidation Step of Diphthamide Biosynthesis in Yeast Requires DPH6, a Gene Identified through Mining the DPH1-DPH5 Interaction Network.
- Published in:
- PLoS Genetics, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.pgen.1003334
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- Publication type:
- Article
Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington's disease models.
- Published in:
- Journal of Molecular Medicine, 2016, v. 94, n. 2, p. 235, doi. 10.1007/s00109-015-1344-5
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- Publication type:
- Article
The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease.
- Published in:
- Journal of Molecular Medicine, 2013, v. 91, n. 6, p. 705, doi. 10.1007/s00109-013-1046-9
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- Publication type:
- Article
Understanding neuronal dysfunction and loss in neurodegenerative disease.
- Published in:
- 2013
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- Publication type:
- Editorial
Parkinson's disease-associated mutations in DJ-1 modulate its dimerization in living cells.
- Published in:
- Journal of Molecular Medicine, 2013, v. 91, n. 5, p. 599, doi. 10.1007/s00109-012-0976-y
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- Publication type:
- Article
The Parkinson's Disease-Linked Protein DJ-1 Associates with Cytoplasmic mRNP Granules During Stress and Neurodegeneration.
- Published in:
- Molecular Neurobiology, 2019, v. 56, n. 1, p. 61, doi. 10.1007/s12035-018-1084-y
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- Publication type:
- Article
Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease.
- Published in:
- 2021
- By:
- Publication type:
- Correction Notice
Publisher Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease.
- Published in:
- 2020
- By:
- Publication type:
- Correction Notice
Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease.
- Published in:
- 2020
- By:
- Publication type:
- Correction Notice
Maternal genotype determines kynurenic acid levels in the fetal brain: Implications for the pathophysiology of schizophrenia.
- Published in:
- 2018
- By:
- Publication type:
- journal article
shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity.
- Published in:
- PLoS Genetics, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pgen.1005995
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- Publication type:
- Article